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Updated: Feb 15, 2026

Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells
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Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells

Published on: July 24, 2019

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組織特異のプロモーターバイバル性は,成人の細胞におけるPRC2の必要性の基礎である

Unmesh Jadhav1, Kodandaramireddy Nalapareddy1, Madhurima Saxena1

  • 1Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

Cell
|May 24, 2016
PubMed
まとめ

ポリコンブ抑制複合体2 (PRC2) は,成体動物における二重メチル化マークを持つ組織特異的な遺伝子を抑制する. PRC2の喪失は異常な遺伝子発現につながり,自己再生組織の欠陥を説明します.

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