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関連する概念動画

The Thyroid Gland01:23

The Thyroid Gland

8.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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甲状腺がん

Maria E Cabanillas1, David G McFadden2, Cosimo Durante3

  • 1Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Lancet (London, England)
|June 1, 2016
PubMed
まとめ
この要約は機械生成です。

甲状腺がんの発生率は 世界的に上昇しています 差別化型甲状腺がんは標準的な治療法で治療できるが,髄膜がんやアナプラスティック型甲状腺がんのような稀なタイプは,進行する病気の特殊なケアと標的治療を必要とします.

さらに関連する動画

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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関連する実験動画

Last Updated: Mar 20, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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科学分野:

  • 腫瘍学
  • 内分泌学

背景:

  • 甲状腺がんは 世界的に深刻な健康問題となっています
  • 差別化された甲状腺がん (DTC) は最も一般的なサブタイプで,標準的な治療は一般的に効果的です.
  • 甲状腺髄性がん (MTC) と アナプラスティック甲状腺がん (ATC) を含む希少なサブタイプは,ユニークな課題を提示します.

研究 の 目的:

  • 甲状腺がんの発生と治療の現状をまとめます
  • 異なる甲状腺癌のサブタイプに対する 異なる管理戦略を強調する.
  • 進行または進行中の甲状腺がんにおける標的治療の役割について議論する.

主な方法:

  • 甲状腺がんの発生率に関する疫学データのレビュー
  • 分化性甲状腺がんの標準治療プロトコルの分析
  • 甲状腺の髄膜がんとアナプラスティックがんの専門的なアプローチの検討
  • 進行した甲状腺がんに対する承認された標的治療法の評価

主要な成果:

  • 甲状腺がんの発生率は 世界中で増加しており 米国女性では5番目に多い癌です
  • DTCの標準的な治療法 (手術と放射性ヨウ素または観察) は,ほとんどの患者にとって有効です.
  • DTCとMTCの標的治療は,進行性のない生存を延ばすことができますが,治療は進行性または症状のある症例に留められています.

結論:

  • 甲状腺がんの効果的な管理は,正確なサブタイプと適切な治療法の選択に依存します.
  • 希少で攻撃的な甲状腺癌のサブタイプを管理するには 専門的な専門知識が不可欠です
  • ターゲティングセラピーは 進行した病気の治療に 利点をもたらしますが 治療法への継続的な研究の必要性を強調しています