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Updated: Mar 20, 2026

Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment
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Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment

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特定のtRNAの調節された発現は遺伝子発現とがんの進行を誘導する

Hani Goodarzi1, Hoang C B Nguyen1, Steven Zhang1

  • 1Laboratory of Systems Cancer Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Cell
|June 4, 2016
PubMed
まとめ

特定の転送RNA (tRNAs) は,遺伝子発現を変化させることで,乳がんの転移を促進する. 上位調節されたtRNAは特定のトランスクリプトの安定性を高め,がんの進行と疾患のアウトカムを促します.

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