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Updated: Mar 20, 2026

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta

Published on: December 5, 2019

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デュアルリングE3アーキテクチャは,APC/Cによるマルチウビキチンとウビキチン鎖の延長を制御する

Nicholas G Brown1, Ryan VanderLinden2, Edmond R Watson1

  • 1Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|June 4, 2016
PubMed
まとめ

アナフェーズ促進複合体/サイクロソーム (APC/C) は,タンパク質のユビキチン化を制御するために異なるE2酵素アーキテクチャを使用する. 特殊な構造により,マルチユビキチン化と結合特有のポリユビキチン鎖の延長が可能である.

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