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Updated: Mar 19, 2026

A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System
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A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System

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双子とグノトビオティックマウスにおける腸内微生物群と粘膜IgA応答の発達

Joseph D Planer1,2, Yangqing Peng1,2, Andrew L Kau1,2

  • 1Center for Genome Sciences &Systems Biology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Nature
|June 10, 2016
PubMed
まとめ

この研究は,乳児の腸内免疫,特に免疫グロブリンA (IgA) が腸内細菌と共にどのように発達するか明らかにしています. IgA反応は早期に家族内で独自に成熟し,その後,食事よりも固有の細菌特性を強調します.

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