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Updated: Mar 8, 2026

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
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Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

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系統的なRNAをデンドリット細胞に送り込むことで,抗ウイルス防御をがん免疫療法に活用する

Lena M Kranz1,2, Mustafa Diken1,3, Heinrich Haas3

  • 1TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.

Nature
|June 10, 2016
PubMed
まとめ

静脈内投与されたRNA- リポプレックス (RNA- LPX) は,活力のあるT細胞応答を in vivo で効果的に標的とする. この新しいワクチンプラットフォームは 強い適応性および先天的な免疫を誘発し 癌の免疫療法に希望を示しています

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