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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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オレフィン製のヌクレオフィルをケトンに非対称的に加える

Yang Yang1, Ian B Perry1, Gang Lu2

  • 1Department of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|June 11, 2016
PubMed
まとめ

この研究は,エナンチオ濃縮アルコールを合成するための新しい銅触媒法を導入しています. このプロセスは,ケトンにステレオ選択的に加えるために容易に入手可能な炭化水素を使用し,スケーラブルで効率的な代替案を提供します.

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