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Updated: Mar 19, 2026

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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Published on: September 8, 2021

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転写活性化の構造的基礎

Yu Feng1, Yu Zhang1, Richard H Ebright2

  • 1Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA.

Science (New York, N.Y.)
|June 11, 2016
PubMed
まとめ

TTHB099 (TAP) のようなクラスIIの転写活性化剤は,RNAポリメラーゼ (RNAP) の相互作用を安定させることで,遺伝子転写を強化する. この構造的研究は,TAPがタンパク質-DNAおよびタンパク質相互作用を通じて転写を開始する方法を明らかにしています.

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