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Updated: Mar 19, 2026

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
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Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

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タンパク質 の 結合,滑り,および DNA の 折り畳み の 間 の ダイナミック な 結合 は,分子 ダイナミクス に よっ て 明らか に なっ た

Cheng Tan1, Tsuyoshi Terakawa2, Shoji Takada1

  • 1Department of Biophysics, Graduate School of Science, Kyoto University , Kyoto 606-8502, Japan.

Journal of the American Chemical Society
|June 17, 2016
PubMed
まとめ

タンパク質がDNAに結合すると その構造に影響を及ぼし 逆もそうです この研究は,バクテリアの構造タンパク質HUおよび他のDNA結合タンパク質における,ポラロン型スライディングと呼ばれる,結合されたスライディングおよび曲げるメカニズムを明らかにした.

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