AMPK-SKP2-CARM1のシグナルカスケードは,オートファギーの転写調節に作用する

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Study of Protein-protein Interactions in Autophagy Research
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Published on: September 9, 2017

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Hi-Jai R Shin1, Hyunkyung Kim1, Sungryong Oh1

  • 1Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University, Seoul, South Korea.

Nature
|June 17, 2016
PubMed
まとめ

共同活性化剤関連アルギニンメチルトランスフェラーゼ1 (CARM1) は,自己消化に不可欠である. 栄養素の飢餓は,ヒストンのメチル化とオートファギーの遺伝子発現を促進する,CARM1を増加させるシグナル軸を活性化させます.

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