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Updated: Mar 19, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

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ユカリオットmRNAの5'-未翻訳領域による翻訳制御

Alan G Hinnebusch1, Ivaylo P Ivanov1, Nahum Sonenberg2

  • 1Group on Cell Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|June 18, 2016
PubMed
まとめ

ユカリオット5'未翻訳領域 (UTR) は,リボソームをメッセンジャーRNA (mRNA) に誘導することによってタンパク質の産生を制御する. 翻訳効率をコントロールするには,上流のオープン・リーディング・フレームとイニシアチブ・ファクターを含む,これらのメカニズムを理解することが重要です.

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