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Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation
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Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Published on: March 14, 2014

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ミトコンドリアの展開タンパク質応答制御マトリックスの前RNA処理と翻訳

Christian Münch, J Wade Harper

    Nature
    |June 29, 2016
    PubMed
    まとめ

    ミトコンドリアのタンパク質の誤折れは,ヒトの細胞における解き放たれたタンパク質反応 (UPRmt) を引き起こす. この反応はチャペロンを増やし,ミトコンドリアの翻訳を減らし,タンパク質の恒常性を維持します.

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