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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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ウイルス 中核 の タンパク質 は 宿主 の 核 細胞 に 結合 し,免疫 システム の 危険 信号 を 隔離 する

Daphne C Avgousti, Christin Herrmann, Katarzyna Kulej

    Nature
    |July 1, 2016
    PubMed
    まとめ

    アデノウイルスタンパク質VIIは,核細胞を結合して宿主染色体の構造を変え,抗ウイルス反応に影響します. このウイルスのタンパク質は,高移動群タンパク質B1 (HMGB1) を隔離し,その放出を防止し,免疫信号を抑制します.

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