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Updated: Mar 18, 2026

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Boris Pasche1, Michael J Pennison2, Barry DeYoung3

  • 1Department of Cancer Biology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina2Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston Salem, North Carolina4Associate Editor, JAMA.

JAMA
|July 6, 2016
PubMed
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No abstract available in PubMed .

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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