Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

8.7K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
8.7K
Role of Amygdala in Memory01:16

Role of Amygdala in Memory

1.5K
The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
1.5K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.4K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.4K
Association Areas of the Cortex01:21

Association Areas of the Cortex

10.3K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
10.3K
Preparedness and Phobias01:09

Preparedness and Phobias

425
Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
425

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Conditioned accumbal dopamine transients forecast individual preference for drug versus natural rewards and compulsive behavior.

Nature neuroscience·2026
Same author

Prefrontal long-range somatostatin inhibitory projections modulate fear expression.

Frontiers in cellular neuroscience·2026
Same author

Multipair phase-modulated temporal interference electrical stimulation combined with fMRI.

Cell systems·2026
Same author

Prefrontal neural geometry of learned cues guides motivated behaviours.

Nature·2026
Same author

[Impact of transcranial magnetic stimulation on depressive symptoms relief in patients with chronic neuropathic pain and comorbid depression: A narrative literature review].

L'Encephale·2025
Same author

Functional and structural profiling of circulation via genetically encoded modular fluorescent probes.

bioRxiv : the preprint server for biology·2025

関連する実験動画

Updated: Mar 18, 2026

Ex Vivo Optogenetic Dissection of Fear Circuits in Brain Slices
11:13

Ex Vivo Optogenetic Dissection of Fear Circuits in Brain Slices

Published on: April 5, 2016

17.2K

前頭前部のニューロンは 恐怖の行動を一時的に制御します

Cyril Dejean, Julien Courtin, Nikolaos Karalis

    Nature
    |July 14, 2016
    PubMed
    まとめ

    背中中前頭皮質 (dmPFC) の神経振動が 恐怖反応のニューロン集合を調整する. この研究は 恐怖行動の正確なタイミングを制御する 段階特有のコーディングメカニズムを明らかにしています

    科学分野:

    • 神経科学
    • 計算神経科学
    • 行動神経科学

    背景:

    • ニューロンの振動と細胞集合は 精密なピークタイミングによる 感覚と認知の処理に不可欠です
    • 感情的行動,特に恐怖における スパイクタイム・コーディングの役割は 未知のままです
    • 背中中前頭前皮質 (dmPFC) は恐怖記憶の表現に不可欠であり,脅威のシグナルをスパイクレートでコード化します.

    研究 の 目的:

    • 恐怖行動における dmPFC のスパイクタイム・コーディングと ニューロン・アセンブリの役割を調査するためです
    • dmPFCのニューロンの振動が 恐怖反応の正確なタイミングに 寄与するかどうかを判断する.

    主な方法:

    • dmPFCにおける単一のユニットとローカルフィールドポテンシャルの記録
    • dmPFCの神経活動による光遺伝的操作
    • 恐怖行動中のニューロンの集合形成と振動活動の分析

    主要な成果:

    • dmPFCにおける条件付きの恐怖表現は ニューロンの機能的な組成の組織と因果的に関連しています
    • dmPFCの4Hzの振動は 恐怖行動中のニューロンのアセンブリの活性化と相関しています
    • 特定の振動段階における光遺伝的抑制は恐怖反応に差異的に影響し,他の段階では促進が起こります.

    さらに関連する動画

    A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior
    09:26

    A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior

    Published on: January 5, 2021

    7.5K
    Trace Fear Conditioning in Mice
    07:02

    Trace Fear Conditioning in Mice

    Published on: March 20, 2014

    34.3K

    関連する実験動画

    Last Updated: Mar 18, 2026

    Ex Vivo Optogenetic Dissection of Fear Circuits in Brain Slices
    11:13

    Ex Vivo Optogenetic Dissection of Fear Circuits in Brain Slices

    Published on: April 5, 2016

    17.2K
    A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior
    09:26

    A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior

    Published on: January 5, 2021

    7.5K
    Trace Fear Conditioning in Mice
    07:02

    Trace Fear Conditioning in Mice

    Published on: March 20, 2014

    34.3K

    結論:

    • dmPFC内でニューロンの集合を動的に制御する 新しい相特有のコーディングメカニズムを特定した.
    • このメカニズムは 恐怖反応のタイミングを 正確に制御し 単純にピークレートの コーディングを超えています
    • この発見は,dmPFCにおける振動ダイナミクスの 感情的行動の時間的制御の重要性を強調している.