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Updated: Mar 17, 2026

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
07:51

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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GluD受容体がシナプスオーガナイザー複合体内に統合される構造的基礎

Jonathan Elegheert1, Wataru Kakegawa2, Jordan E Clay1

  • 1Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

Science (New York, N.Y.)
|July 16, 2016
PubMed
まとめ

研究者らは,Cbln1がシナプスでイオノトロプ的グルタミン酸受容体 δ2 (GluD2) とβ-ニューレキシン 1 (β-NRX1) を橋渡しする方法を明らかにした. この相互作用は,D-セリン媒介のシグナル伝達,小脳シナプス機能,およびマウスの運動調整に極めて重要です.

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Presynapse Formation Assay Using Presynapse Organizer Beads and “Neuron Ball” Culture10:17

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