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Updated: Jul 9, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
16:19

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

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アイソメリックに純粋なテトラメチルロダミン電圧レポーター

Parker E Deal1, Rishikesh U Kulkarni1, Sarah H Al-Abdullatif1

  • 1Department of Chemistry, ‡Department of Molecular & Cell Biology, and §Helen Wills Neuroscience Institute, University of California , Berkeley, California 94720, United States.

Journal of the American Chemical Society
|July 19, 2016
PubMed
まとめ

研究者らは細胞膜ポテンシャルを正確に検出するための新しいロダミン電圧レポーター (RhoVR) を開発した. これらの敏感で明るい光染料は 脳科学の研究に 改善されたイメージングと 幅広い適用性を提供します

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Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

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Purification and Reconstitution of TRPV1 for Spectroscopic Analysis

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Potentiometer01:30

Potentiometer

Voltage and current measurements using a standard voltmeter and ammeter alter the circuit being measured either by drawing or resisting the current flow, which introduces uncertainties in the measurements. Null measurements balance the voltages so that no current flows through the measuring device and, therefore, no alterations occur in the measured circuit.
Suppose the emf of a battery needs to be measured. If the battery is directly connected to a standard voltmeter, the measured quantity is...
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Voltage Dividers01:14

Voltage Dividers

In electrical circuits, resistors can be connected in series, sequentially linked one after the other. In a series configuration, the same current flows through each resistor. Ohm's law is a fundamental principle to understand the behavior of resistors in series. It expresses the voltage across these resistors in terms of the current and resistance.
Kirchhoff's voltage law implies that the sum of the voltages across the resistors in series equals the source voltage. This means that the current...
Voltage Doubler Circuit01:23

Voltage Doubler Circuit

A voltage doubler circuit integrates two main components: a clamping section and a rectifier section. The clamping section consists of a capacitor (C1) and a diode (D1), whereas the rectifier section is equipped with another diode (D2) and capacitor (C2). This circuit produces an output voltage with twice the amplitude of the sinusoidal input voltage.
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Biasing of FET

Biasing a Junction Field Effect Transistor (JFET) is crucial for setting operational parameters and ensuring efficient functioning in electronic circuits. JFETs are characterized by using a single carrier type in N-channel or P-channel configurations, where the channel is surrounded by PN junctions. These junctions are central to the device's ability to control current flow.
In an N-channel JFET, the structure consists of N-type material forming the channel on a P-type substrate, with the gate...
Generator Voltage Control01:21

Generator Voltage Control

Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...