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Updated: Mar 17, 2026

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
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拡張核塩基選択性によるヒトゲノムDNA配列の分離

Preeti Rathi1, Sara Maurer1, Grzegorz Kubik1

  • 1Department of Chemistry and Chemical Biology, Technical University of Dortmund , Otto-Hahn-Str. 6, 44227 Dortmund, Germany.

Journal of the American Chemical Society
|July 19, 2016
PubMed
まとめ

研究者は,ヒトゲノムから直接5-メチルサイトシン (5mC) のような表遺伝的改変を含むDNA配列を正確に分離し定量化するために,エンジニアリングされた転写活性化器のようなエフェクター (TALEs) を使用して新しい方法を開発しました.

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