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関連する概念動画

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

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Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
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Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

434
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
434
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

143
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
143
Healing II: Complications01:24

Healing II: Complications

37
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
37
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

33
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
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Updated: May 2, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

11.3K

セルライト: 概要

Adam B Raff1, Daniela Kroshinsky1

  • 1Harvard Medical School, Massachusetts General Hospital, Boston.

JAMA
|July 20, 2016
PubMed
まとめ
この要約は機械生成です。

細胞炎は一般的な皮膚感染症で 臨床的に診断されます 初期治療は,高リスクの患者を対象として,ストレプトコックスとメチチリンに敏感な黄色のステーキ菌を標的とする. 危険因子に対処することで 再発を防ぐことができます

関連する実験動画

Last Updated: May 2, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

11.3K

科学分野:

  • 皮膚科
  • 感染症
  • 公衆衛生

背景:

  • セルロース炎は,皮膚の深い部位と皮下組織に影響を与える細菌性皮膚感染症です.
  • アメリカでは毎年65万人を超える患者が診察され,医療費が大きく負担されています.
  • 原因となるバクテリアは,ほとんどの場合,培養不可能な性質のため,しばしば特定されません.

研究 の 目的:

  • 細胞炎の診断基準をまとめました
  • 細胞炎の治療のガイドラインを 提供するためです
  • 再発を予防する要因に対処する重要性を強調する.

主な方法:

  • 診断は赤血腫,暖かさ,繊細さ,腫れを含む臨床的な表現に依存します.
  • 経験的な抗生物質の選択は,ストリプトコックスや 黄金球菌のような一般的な病原体を考慮します.
  • 治療期間は通常5日であり,臨床反応に応じて延長されます.

主要な成果:

  • セルロース炎の最も一般的な病原体とは ストレプトコッカスと ステーフィロコッカス・オーレウスです
  • 治療は最初はメチシリン感受性S. aureus (MSSA) で,リスク集団ではメチシリン耐性S. aureus (MRSA) に拡大する必要があります.
  • 抗生物質治療の5日間は通常十分で,症状が持続する場合はより長いコースです.

結論:

  • 細胞炎の診断は主に臨床的であり,患者の病歴と身体検査に基づいています.
  • 標準的な治療は ストレプトコッカスとMSSAを標的とするものです
  • 治療の失敗は,耐性生物,模倣性疾患,または根本的な健康問題に対する再評価を必要とします.