関連する実験動画

Updated: Mar 17, 2026

Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
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Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

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マウスの非活性X染色体の構造組織

Luca Giorgetti, Bryan R Lajoie, Ava C Carter

    Nature
    |July 21, 2016
    PubMed
    まとめ

    X染色体不活性化 (XCI) は,不活性なX染色体 (Xi) を再構成する. Xist RNAとDXZ4の境界は,構造を保持する脱出遺伝子を除いて,X構造にとって極めて重要であり,メガドメインを形成し,DNAのアクセシビリティを減少させます.

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    In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
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