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Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization
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CD47 阻害抗体はファゴシトーシスを回復し,動脈硬化症を予防する

Yoko Kojima, Jens-Peter Volkmer, Kelly McKenna

    Nature
    |July 21, 2016
    PubMed
    まとめ

    動脈硬化症は,増加したCD47による病気の細胞の除去が妨げられる. CD47を阻害すると,細胞クリアランスが回復し,小鼠モデルでの動脈硬化が減少し,潜在的な治療目標が明らかになる.

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