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Updated: Mar 17, 2026

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans
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Published on: September 7, 2021

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進化的に保存された経路がプロテアソームのホメオスタシスを制御する

Adrien Rousseau, Anne Bertolotti

    Nature
    |July 28, 2016
    PubMed
    まとめ

    保存されたシグナル伝達経路は プロテアソムのレベルを調節する. TORC1を阻害すると,Mpk1が活性化され,ストレス下での細胞生存のためのプロテアソーム成分が増加します. この経路は哺乳類に保存されています

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