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Updated: Mar 16, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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Published on: January 13, 2017

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Streptomyces platensis CB00739 のエントコパリル二酸化合成酵素 PtmT2 の構造,細菌のII型ディテルペン合成酵素

Jeffrey D Rudolf1, Liao-Bin Dong1, Hongnan Cao2

  • 1Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|August 5, 2016
PubMed
まとめ

この研究は,細菌の第2型ディテルペン合成酵素 (DTS) 構造であるPtmT2を初めて明らかにした. この発見は,テルペノイド生物合成と細菌におけるテルペン合成酵素 (TSs) の進化の理解を前進させる.

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