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Updated: Mar 16, 2026

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人間の20Sプロテアソームの阻害メカニズムにより,次世代の阻害剤の設計が可能である

Jil Schrader1, Fabian Henneberg1, Ricardo A Mata2

  • 1Department of Structural Dynamics, Max Planck Institut für biophysikalische Chemie, Am Fassberg 11, D-37077 Göttingen, Germany.

Science (New York, N.Y.)
|August 6, 2016
PubMed
まとめ

人間の20Sプロテアソムの高解像度構造とそのがん薬複合体は,抑制メカニズムに関する新しい洞察を明らかにしています. この知識は,がん治療のための次世代のプロテアソーム阻害剤の開発を導くことができます.

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