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分子変形剤は,病的な結晶の成長抑制のメカニズムを明らかにする

Jihae Chung, Ignacio Granja, Michael G Taylor

    Nature
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    PubMed
    まとめ

    シトラートとヒドロキシシトラートは,新しいメカニズムで,腎臓石の原因であるカルシウムオキシラート結晶を溶かすことができます. ハイドロキシシトラートは尿で排出され,結晶形成を効果的に抑制し,腎石治療の可能性があることを示唆しています.

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