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急性心筋梗塞
Grant W Reed1, Jeffrey E Rossi1, Christopher P Cannon2
1Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.
Lancet (London, England)
|August 10, 2016
まとめ
急性心筋梗塞 (AMI) の管理は,ST上昇と非ST上昇MIを同じように治療することによって簡素化されます. 再輸血,抗血小板治療,二次予防の進歩は,この主要な死因の結果を改善しています.
科学分野:
- 心臓病科
- 内科 医学
- 公衆衛生
背景:
- 急性心筋梗塞 (AMI) は,世界的な罹病率と死亡率の主な原因です.
- 改善が進んでいるにもかかわらず AMIは 世界的に重要な健康問題であり続けています
- 管理のためには,従来のST高さMIとST高さMI以外の分類を簡素化することができる.
研究 の 目的:
- AMIの病理生理学,流行病学,および近代的な管理をレビューする.
- AMIの再注射戦略と薬理学的治療における最近の進歩を強調する.
- AMI管理に統一されたアプローチを強調する.
主な方法:
- AMIの病理生理学と疫学に関する現在の文献のレビュー.
- リスクの階層化と侵入的戦略の動向の分析
- 抗血小板薬,抗凝固薬,スタチン療法における進歩の評価
- 経皮冠動脈介入とフィブリノリシスを含む現代的な再注血技術についての議論
主要な成果:
- 過去10年間でAMIの予後が 大きく進歩しました
- 侵襲的戦略の活用と迅速な再血管化
- 抗血小板薬と抗凝固薬の効能が向上した.
- スタチンのような二次予防措置の採用を拡大する
結論:
- 簡潔で統一された管理アプローチは実現可能で有益です.
- AMIの結果を改善するために,再注射と薬剤療法における継続的な進歩は極めて重要です.
- 効果的な二次予防戦略は,長期的な罹病率と死亡率を減らすために不可欠です.
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