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Updated: Mar 16, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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炭酸性マクロラクトニゼーションによる (-) - スピノシンAの総合成

Yu Bai1, Xingyu Shen1, Yong Li1

  • 1Department of Chemistry and Center for Cancer Research, Purdue University , West Lafayette, Indiana 47907, United States.

Journal of the American Chemical Society
|August 12, 2016
PubMed
まとめ

研究者は,有機殺虫剤スピノサドの重要な成分である (-) - スピノシンAの効率的な全合成を達成しました. この突破により,殺虫剤耐性に対抗するスピノシン類の製造が可能になった.

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