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電圧ゲートされたK+チャネルEag1の構造は,代替電圧感知メカニズムを示している

Jonathan R Whicher1, Roderick MacKinnon2

  • 1Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.

Science (New York, N.Y.)
|August 13, 2016
PubMed
まとめ

哺乳類のK(v) 10.1 (Eag1) チャンネルの構造は,新しい電圧依存のゲートメカニズムを明らかにする. カルモジュリンがS4-S5リンクヤーに結合すると,電圧センサーの位置に関係なく,カリウム孔が閉まります.

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