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Updated: Mar 16, 2026

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
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単一のアスパルテートは,ヘッジホッグの自動処理における2つの触媒ステップを調整する

Jian Xie, Timothy Owen1, Ke Xia

  • 1Department of Chemistry, Binghamton University, State University of New York , 4400 Vestal Parkway East, Binghamton, New York 13902, United States.

Journal of the American Chemical Society
|August 17, 2016
PubMed
まとめ

ヘッジホッグ (Hh) の重要なアスパルテート残留物 (D46) は,コレステロールの修正に不可欠なタンパク質の自己処理をシグナルする. この残留物は2つの触媒のステップを結合し,効率的なHh信号経路の活性化を保証します.

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