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副作用が軽減されたオピオイド鎮痛剤の構造に基づく発見

Aashish Manglik1, Henry Lin2, Dipendra K Aryal3

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|August 18, 2016
PubMed
まとめ

研究者はPZM21という新しい化合物を発見し,痛みを和らげるためにミュオピオイド受容体 (μOR) を活性化する. モルヒネとは違って PZM21は 呼吸阻害のような副作用を最小限に抑えながら 強力な鎮痛剤を提供します

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