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Updated: Mar 16, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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キノリネート合成の結晶構造は,基質アナログ,凝縮介質,基質派生産物と複合している

Anne Volbeda1, Claudine Darnault1, Oriane Renoux1

  • 1Metalloproteins Unit, Institut de Biologie Structurale, CEA, CNRS, Université Grenoble-Alpes , 71, Avenue des Martyrs, 38044 Grenoble Cedex 9, France.

Journal of the American Chemical Society
|August 23, 2016
PubMed
まとめ

この研究では,重要な中間物質と相互作用する NadA 酵素の結晶構造が明らかになりました. これらの発見は,NADコファクターの生成に不可欠なキノリニン酸 (QA) の合成におけるNADの触媒メカニズムを明らかにする.

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