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HER2発現は,循環する乳がん細胞内の動的機能的状態を識別する

Nicole Vincent Jordan1, Aditya Bardia1,2, Ben S Wittner1,2

  • 1Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

Nature
|August 25, 2016
PubMed
まとめ

進行した乳がん細胞は,HER2陽性特性を発達させ,薬剤耐性を引き起こす. HER2 経路と Notch 経路の両方を標的にすることで,腫瘍の成長を抑制することが期待されています.

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