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PGC1α媒介の転写軸はメラノーマの転移を抑制する

Chi Luo1, Ji-Hong Lim1, Yoonjin Lee1,2

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 1, 2016
PubMed
まとめ

PGC1αは,ID2とTCF4を調節することによって,メラノーマの転移を抑制する. この経路は,代謝の役割とは異なり,皮膚がん治療の新たな治療目標を提供します.

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