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Updated: Mar 15, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
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カイナート亜型グルタミン酸受容体無敏感化の構造的基礎

Joel R Meyerson1, Sagar Chittori1,2, Alan Merk1

  • 1Laboratory of Cell Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892, USA.

Nature
|September 1, 2016
PubMed
まとめ

研究者らはカイナート受容体GluK2の構造を無感化状態で明らかにした. リンガンド結合ドメインの 新しい"無敏感化環"が これらの受容体が 閉じる仕組みを説明し 脳機能や病気を理解するのに 極めて重要です

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