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エンドセリンETB受容体の活性化メカニズム エンドセリン-1

Wataru Shihoya1,2,3, Tomohiro Nishizawa3,4, Akiko Okuta2

  • 1Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan.

Nature
|September 6, 2016
PubMed
まとめ

エンドセリンB受容体に関する構造的な洞察は,それがどのようにエンドセリン-1に結合するかを明らかにし,肺動脈高血圧のような疾患に対する新しい治療標的を提供している.

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