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Updated: May 8, 2026

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Cécile Le Pechoux1, Frederic Dhermain1, Benjamin Besse2

  • 1Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif 94800, France.

Lancet (London, England)
|September 9, 2016
PubMed
まとめ

No abstract available in PubMed .

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Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...