病気 に 耐える 方法: 脳 に 良い 食べ物 を 与え て ください
1Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Cell
|September 10, 2016
まとめ
病気は食欲低下を引き起こし 細胞のストレスに対する 代謝の必要性を変化させます これは細菌感染とウイルス感染の間の 耐性に影響を及ぼし ホストの防御戦略を最適化します
科学分野:
- 免疫学
- 代謝経路について
- ホストと病原体の相互作用
背景:
- 感染時の宿主の防御戦略は しばしば餌の行動の変化を含みます
- 病原菌に対する宿主の反応を最適化することを目指しています.
研究 の 目的:
- 病気に起因する食欲低下が 細胞のストレス適応の代謝要件にどのように影響するか調査する.
- バクテリア感染とウイルス感染の間の病気の耐性に対する食欲低下の影響の違いを決定する.
主な方法:
- 感染時の食欲低下に関連した代謝変化の分析
- アノレキシアの条件下で細菌やウイルスの病原体に対する宿主耐性の比較評価
主要な成果:
- 病気に起因する食欲低下は 細胞のストレス反応に対する代謝の要求を 異なる形で形作ります
- アノレキシアは,感染が細菌性かウイルス性かによります.
結論:
- 病気の時の食生活の変化は 異なった代謝結果をもたらします
- これらの代謝変化を理解することは,さまざまな種類の感染症に対する耐性を向上させるための標的治療の開発に不可欠です.
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