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X線構造はヒトP2X(3) 受容器ゲートサイクルと対抗作用を定義する

Steven E Mansoor1,2, Wei Lü1, Wout Oosterheert1

  • 1Vollum Institute, Oregon Health &Science University, Portland, Oregon 97239, USA.

Nature
|September 15, 2016
PubMed
まとめ

研究者は最初のヒトP2X3受容体の構造を明らかにし,開いた状態と閉じた状態を詳細に説明しました. これらの発見はATPゲートイオンチャネルメカニズムを明らかにし,新しい治療薬の設計にインフォームします.

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