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Updated: Mar 14, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

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バクテリアの翻訳初期におけるIF3とtRNAの大規模な移動

Tanweer Hussain1, Jose L Llácer1, Brian T Wimberly2

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Cell
|September 24, 2016
PubMed
まとめ

バクテリアの翻訳開始には,スタートコドン認識を容易にする3つの開始因子 (IFs 1-3) が含まれる. この研究では,これらの因子を視覚化するために,冷凍電子顕微鏡 (cryo-electron microscopy,cryoEM) を用いて,30Sリボソームサブユニット上のイニシアターtRNAおよびmRNAの位置づけにおけるそれらの役割を明らかにした.

キーワード:
IF1 についてIF2 についてIF3 についてクリオ・エムfMet-tRNA について開始するリボソームスタートコドン構造物翻訳

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