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Updated: Nov 13, 2025

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異なる治療介入におけるLDL-Cの低下と心血管リスクの減少との関連:体系的レビューとメタ解析

Michael G Silverman1, Brian A Ference2, Kyungah Im1

  • 1TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

JAMA
|September 28, 2016
PubMed
まとめ

スタチンはLDL受容体の発現を増加させる治療法であり,LDL-Cを低下させるごとに,同様の心血管リスクの減少を示している. LDL- Cのレベルを下げることは,主予防と二次予防の両方で主要な冠動脈イベントの減少と関連しています.

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