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Updated: Mar 14, 2026

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
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Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics

Published on: May 14, 2016

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XPO1に依存する核の輸出は,KRAS変異性肺がんにおける薬剤可能な脆弱性である

Jimi Kim1, Elizabeth McMillan1, Hyun Seok Kim2

  • 1Department of Cell Biology, UTSW Medical Center, Dallas, Texas 75390, USA.

Nature
|September 30, 2016
PubMed
まとめ

KRAS変異性肺がんの 核輸出をターゲットにすると 望ましい結果が出ています XPO1 (エクスポートイン1) を阻害することは,選択された患者でYAP1- TEAD阻害剤による抵抗を克服する合成- 致死的な戦略を提供します.

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