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Updated: Mar 14, 2026

Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
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Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

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機能的代謝は酵母生物合成レギュロームを記述する

Michael Mülleder1, Enrica Calvani1, Mohammad Tauqeer Alam2

  • 1Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK; The Francis Crick Institute, Mill Hill Laboratory, Mill Hill, London NW7 1AA, UK.

Cell
|October 4, 2016
PubMed
まとめ

この研究は酵母遺伝子の代謝相互作用をマッピングし,遺伝子の3分の1以上が生物合成に影響を及ぼすことを明らかにしました. メタボロミックシグネチャーは,特徴づけられていない遺伝子の機能を特定し,細胞の調節を理解するのに役立ちます.

キーワード:
アミノ酸機能的な遺伝子アノテーション機能的メタボロミクスマススペクトロメトリーメタボリズムラパミシン (TOR) の標的未知の遺伝子機能膀を媒介する輸送イーストの遺伝子削除の収集

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