ジカウイルス:免疫とワクチン開発
Theodore C Pierson1, Barney S Graham2
1Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Cell
|October 4, 2016
まとめ
ジカウイルスの流行は,重度の神経発達障害を防ぐために,迅速なワクチンの開発を必要とした. 有望なワクチン候補は,ジカウイルスの感染と病気を制御する希望を提供します.
科学分野:
- ウイルス学
- 免疫学
- 公衆衛生
背景:
- アメリカとカリブ海でジカウイルスの出現は,公衆衛生に重大な脅威をもたらしました.
- 妊娠中のジカウイルス感染は 乳児に重度の神経発達障害を引き起こす可能性があります
研究 の 目的:
- ジカウイルスワクチンへの緊急の必要性を要約します
- ジカの免疫とワクチン開発の進歩を強調する.
主な方法:
- ジカウイルスの免疫に関する最近の科学文献のレビュー.
- 進行中のジカワクチン開発の分析
主要な成果:
- ジカウイルスの免疫学を理解するうえで 重要な進展がみられた.
- いくつかの有望なジカワクチン候補が開発されています.
結論:
- ジカウイルスに対する予防策は 実現可能になってきています
- 継続的な研究と開発は,世界の健康安全保障に不可欠です.
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