病理生理学,研究課題,および煙吸入による傷害の臨床管理
Perenlei Enkhbaatar1, Basil A Pruitt2, Oscar Suman3
1Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA.
Lancet (London, England)
|October 7, 2016
まとめ
煙の吸入による傷は重度の火傷の後に 症状を著しく悪化させる. このレビューは,その病理生理学,証拠に基づいた治療法,そして診断と管理のための将来の方向性をカバーします.
科学分野:
- 医学 研究
- 灼熱 治療
- 肺科
背景:
- 煙の吸入による損傷は重度の火傷患者の罹患率と死亡率を増加させる重要な要因です.
- その影響にもかかわらず,研究は主に臨床前試験に限られています.
- 診断,重症度分類,および予後については,世界的に合意が欠けている.
研究 の 目的:
- 煙の吸入による傷害の病理学に関する現在の理解をレビューする.
- 煙の吸入による傷害の証拠に基づく治療法について議論する.
- 煙の吸入による傷害の診断と管理における課題と将来の方向性を特定する.
主な方法:
- 煙の吸入による傷害に関する既存の研究の文献レビュー
- 現在の診断と治療方法の分析
- 病理生理学,治療,将来の研究ニーズに関する情報の合成.
主要な成果:
- 煙の吸入による損傷の病理生理学は複雑で,熱と化学的攻撃を含みます.
- 治療戦略は大きく異なっており 標準化されたプロトコルが必要であることを強調しています
- 診断基準と予後指標には大きなギャップがある.
結論:
- 煙の吸入による傷害の管理には 理解の向上と標準化されたアプローチが不可欠です
- 診断と治療を進めるためにさらなる研究が必要です.
- 現在の治療の変異性に対処することで,患者のアウトカムが改善されます.
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