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D2Oによるα-キラルアミンのステレオレテンティブデュテレーション

Lillian V A Hale1, Nathaniel K Szymczak1

  • 1Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|October 7, 2016
PubMed
まとめ

研究者は,ルーテニウム触媒と重水を使用して,プライマリアミンの直接デュテレーションの方法を開発しました. このプロセスは,アルファ炭素で高デュテリウム組み込みを達成し,キラルアミンの立体化学を保持します.

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