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Updated: Mar 14, 2026

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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ホスト-プロトゾア相互作用 炎症体の活性化により粘膜感染症から保護する

Aleksey Chudnovskiy1, Arthur Mortha1, Veronika Kana1

  • 1Department of Oncological Science, Icahn School of Medicine at Mount Sinai, 1475 Madison Avenue, New York, NY 10028, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1475 Madison Avenue, New York, NY 10028, USA; The Immunological Institute, Icahn School of Medicine at Mount Sinai, 1475 Madison Avenue, New York, NY 10028, USA.

Cell
|October 8, 2016
PubMed
まとめ

原生体Tritrichomonas musculisは,炎症ソームを活性化し,IL-18を誘発することによって,細菌感染に対する粘膜免疫を強化する. しかし 大腸炎や結腸直腸腫瘍などの 炎症性疾患のリスクも増加します

キーワード:
IL-18 についてIL-1b についてトリチコモナス・マスキュリス大腸がんコメンサル・プロティスト腸の dendritic 細胞腸内マクロファージ炎症ゾーム腸内細菌感染症微生物群

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