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Updated: Mar 13, 2026

Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans
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Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans

Published on: November 26, 2017

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タンパク質の安定性に関する運動分析により,年齢による劣化が明らかになった

Erik McShane1, Celine Sin2, Henrik Zauber1

  • 1Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str.10, 13092 Berlin, Germany.

Cell
|October 11, 2016
PubMed
まとめ

タンパク質の分解は必ずしも指数関数的なものではありません. 多くのタンパク質は若いうちに安定性が低下し,年齢とともに安定性が高くなり,タンパク質複合体の形成と多量調節に影響を与えます.

キーワード:
アヌプロイドバイオオルトゴンアルアミノ酸のタグ付け遺伝子複製数の変化メタボリックラベル翻訳後の検査タンパク質複合体の組成タンパク質の分解プロテオミクスパルスチェイス実験トライソミー

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