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Updated: Mar 13, 2026

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デウビキチナーゼのLys11-ポリウビキチン特異性の分子基礎

Tycho E T Mevissen1, Yogesh Kulathu1, Monique P C Mulder2

  • 1Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.

Nature
|October 13, 2016
PubMed
まとめ

セザンヌデウビキチナゼ (OTUD7B) は,Lys11結合ポリユビキチン鎖を特に標的とする. この特異性は,ユビキチンによる構造変化によって達成され,ユビキチンコードの複雑な詳細が明らかになる.

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