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A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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遠隔C−H結合の触媒性アルキル化は,陽子結合電子移転によって可能である

Gilbert J Choi1, Qilei Zhu1,1, David C Miller1

  • 1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.

Nature
|October 13, 2016
PubMed
まとめ

研究者らは,陽子結合電子移転を用いて,アミド内の強い窒素-水素結合を断ち切る新しい触媒方法を開発した. これは,直接的な炭素-炭素結合の形成を可能にし,アミンを含む分子の合成を簡素化します.

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