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Updated: Mar 13, 2026

Measuring RAN Peptide Toxicity in C. elegans
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Measuring RAN Peptide Toxicity in C. elegans

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C9orf72 ディペプチドリピート 膜のない器官の組立,動力,機能を損なう

Kyung-Ha Lee1, Peipei Zhang1, Hong Joo Kim1

  • 1Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|October 22, 2016
PubMed
まとめ

ALS/FTDにおけるC9ORF72の再発は,細胞のコンパートメントを破壊する有毒なタンパク質を生成します. アルギニンを含むディペプチドリピートタンパク質は,膜のない臓器細胞と相互作用し,その機能を変化させます.

キーワード:
C9ORF72 についてアミオトロフィック・ラテラル・スクレロスディペプチドを繰り返す膜のない器官中核フェーズ分離ストレス・グラニュル

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